Publications

Recent publications

  1. Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex. Huynen MA, Mühlmeister M, Gotthardt K, Guerrero-Castillo S, Brandt U. Biochim Biophys Acta. 2015 Oct 15. pii: S0167-4889(15)00362-6.

  2. Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Birkenmeier K, Dröse S, Wittig I, Winkelmann R, Käfer V, Döring C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML. Int J Cancer. 2015 Nov 23. [Epub ahead of print] PubMed PMID: 26595876.

  3. Accessory NUMM (NDUFS6) subunit harbors a Zn-binding site and is essential for biogenesis of mitochondrial complex I. Kmita K, Wirth C, Warnau J, Guerrero-Castillo S, Hunte C, Hummer G, Kaila VRI, Zwicker K, Brandt U, Zickermann V. PNAS. 2015, epub ahead of print, doi:10.1073/pnas.1424353112.

  4. Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I. Zickermann V, Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C, Brandt U. Science. 2015 Jan 2;347(6217):44-9.

  5. Generator-specific targets of mitochondrial reactive oxygen species. Bleier L, Wittig I, Heide H, Steger M, Brandt U, Dröse S. Free Radic Biol Med. 2015 Jan;78:1-10.

  6. NOVA: a software to analyze complexome profiling data. Giese H, Ackermann J, Heide H, Bleier L, Dröse S, Wittig I, Brandt U, Koch I. Bioinformatics. 2015 Feb 1;31(3):440-1.

  7. The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity.
    Angerer H, Radermacher M, Małkowska M, Steger M, Zwicker K, Heide H, Wittig I, Brandt U, Zickermann V. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5207-12.

  8. Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex. Heide H, Bleier L, Steger M, Ackermann J, Dröse S, Schwamb B, Zörnig M, Reichert AS, Koch I, Wittig I, Brandt U. Cell Metab. 2012 Oct 3;16(4):538-49.

  9. A two-state stabilization-change mechanism for proton-pumping complex I. Brandt U. Biochim Biophys Acta. 2011 Oct;1807(10):1364-9.

  10. Functional dissection of the proton pumping modules of mitochondrial complex I. Dröse S, Krack S, Sokolova L, Zwicker K, Barth HD, Morgner N, Heide H, Steger M, Nübel E, Zickermann V, Kerscher S, Brutschy B, Radermacher M, Brandt U. PLoS Biol. 2011 Aug;9(8):e1001128.

  11. Functional modules and structural basis of conformational coupling in mitochondrial complex I. Hunte C, Zickermann V, Brandt U. Science. 2010 Jul 23;329(5990):448-51.

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